The Black Flash of the "current" Flash Reborn mini-series might be a universe-level threat. It's hard to tell since a story about the fastest men alive has ground to a halt. (Hence, "current" being in quotes.) Otherwise...no. Not as far as I can figure. About the closest any Flash comes is the Anti-Monitor but that certainly is not a Flash-specific villain.
I haven't been reading Flash Reborn yet, I figured I would read it once it was collected. I trust Geoff Johns as a writer immensely. How has it been so far (despite coming to a halt)?
One of Wally's villains, the K%lg%re, I could see becoming a universe-level treat, if left unchecked... almost like the Borg. (Well, galaxy-level, I guess).
Flash tends not to operate at that level, though... his main job is to protect his city and his planet.
K%lg%ore is basically a sentient computer virus, introduced during the early days of Wally's book (issue 4, i think) and has appeared a few times since then. From what I recall, he's very similar to the JLA villain, the Construct. The basic strategy to defeat him seems to be isolating him from technology (though he's also possessed people -- Linda Park, particularly) -- essentially setting up a firewall. The more he spreads, the more difficult he is to contain, and the more powerful he gets.
Another early-Wally-era character who could be a much bigger threat (had he not reformed into a friendly supporting character pretty much immediately) is Chunk -- a guy living with a black hole inside him, who can suck anything in proximity into another universe. As with K%lg%re, the more the black hole sucks in, the stronger it becomes. Eventually, one supposes, there would be a tipping point.
There's also Big Sir, a latter-day Barry villain so awful that, were he ever to show up again, DC comics might stop publishing out of pure shame as powerful as a million exploding suns.
Ah, Big Sir. I don't know about recent appearances but he was part of the Giffen-era Justice League Injustice League, the whole of which reformed for one "glorious" moment as the Justice League Antarctica where they fought a flock of killer penguins.
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Flash tends not to operate at that level, though... his main job is to protect his city and his planet.
I'm not familiar with this K%lg%re character at all though.
Any more info. on him?
DC Database
Another early-Wally-era character who could be a much bigger threat (had he not reformed into a friendly supporting character pretty much immediately) is Chunk -- a guy living with a black hole inside him, who can suck anything in proximity into another universe. As with K%lg%re, the more the black hole sucks in, the stronger it becomes. Eventually, one supposes, there would be a tipping point.
There's also Big Sir, a latter-day Barry villain so awful that, were he ever to show up again, DC comics might stop publishing out of pure shame as powerful as a million exploding suns.